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*Brain And Cognitive Functions

Migdalis IN, Kalantzis L, Samartzis M, Kalogeropoulou K, Nounopoulos C, Bouloukos A

Wark et al

Pharmacological targeting of CHAC1-mediated processes therefore represents a rational therapeutic strategy, potentially disrupting the cycle of GSH depletion, ER stress amplification and iron-dependent peroxidation that drives neuronal loss